Antimicrobial lock therapy for catheter-related bacteraemia among patients on maintenance haemodialysis

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Antimicrobial lock therapy for catheter-related bacteraemia among patients on maintenance haemodialysis.

Sir, In reference to the review on use of antibiotic locks to treat colonized central venous catheters by Berrington & Gould, 1 we report the results of antibiotic lock therapy (ALT) in our haemodialysis unit. Although this technique was first used more than a decade ago, optimal dose, duration and choice of the agent are still not clear. Reports of the efficacy of ALT in oncology settings, par...

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Antibiotic lock solutions for the prevention of catheter-related bacteraemia in haemodialysis patients.

OBJECTIVE To investigate the effect of antibiotic lock solutions for preventing catheter-related bacteraemia in patients receiving haemodialysis. DESIGN Retrospective study. SETTING University teaching hospital, Hong Kong. PATIENTS Consecutive patients from March 2006 to April 2007 who had central venous catheter insertion for haemodialysis in our centre were included in this historically...

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Catheter-related bacteraemia in haemodialysis patients with HIV infection.

BACKGROUND Tunnelled catheters are used for dialysis in over 25% of haemodialysis (HD) patients and are a major risk factor for bacteraemia. HIV-positive patients may be at particularly increased risk of catheter-related bacteraemia (CRB) due to their immunocompromised state. The present case-controlled study compared catheter-related bacteraemia with HIV-positive and HIV-negative haemodialysis...

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Preventing haemodialysis catheter-related bacteraemia with an antimicrobial lock solution: a meta-analysis of prospective randomized trials.

BACKGROUND Catheter-related bacteraemia (CRB) is a major cause of morbidity and mortality in haemodialysis patients. Interdialytic locking of catheters with antimicrobial agents has recently been investigated for the prevention of CRB. We performed a meta-analysis of randomized controlled trials (RCT) to determine the efficacy of antimicrobial lock solutions (ALS) in the prevention of CRB in ha...

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Taurolidine-citrate-heparin catheter lock solution reduces staphylococcal bacteraemia rates in haemodialysis patients.

BACKGROUND Infection is second only to cardiovascular disease as a cause of death in the haemodialysis (HD) population. AIM : To assess the effect of introducing catheter lock solution taurolidine-citrate-heparin to all tunnelled central venous catheters (TCVCs) on staphylococcal bloodstream infection rates in patients on chronic HD. DESIGN Observational, prospective analysis of the inciden...

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ژورنال

عنوان ژورنال: Journal of Antimicrobial Chemotherapy

سال: 2002

ISSN: 1460-2091

DOI: 10.1093/jac/dkf183